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KMID : 0043319970200020197
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Archives of Pharmacal Research
1997 Volume.20 No. 2 p.197 ~ p.199
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Synthesis of 1-(2-Naphthoyl) Benzotriazoles as Photoactivated DNA Cleaving Agents
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Yang Jae-Wook
Wender Paul-A.
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Abstract
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In conclusion, benzotriazole analogs prepared in this research showed strong possibility to be photochemically activated DNA cleaving agents. Electrophilic groups such as haloacetoxy groups on the alkyl chain of benzotriazole analogs promote the DNA cleaving ability. Synthesis of 1-(2-Naphthoyl) Benzotriazoles.
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KEYWORD
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benzotriazole, benzotriazole-5-carboxylic acid, photoactivated DNA cleaving agents
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